Most accurate biopsy method for microcalcifications?
Meet the Experts
Jennifer Griggs, M.D., M.P.H. is a medical oncologist specializing in the treatment of breast cancer, dedicated to developing programs that improve the well-being of women treated for breast cancer.
Question from Anna975: What is the most accurate biopsy method that can be used for a group of 10-15 microcalcifications in one area?
- Answer —Jennifer Griggs, M.D., M.P.H.:
Microcalcifications, which are calcium deposits within the breast, often prompt a further evaluation with a procedure such as a biopsy. There are many different types of biopsy needles, and as long as the specimen is large enough and taken from the correct place, I don't believe there is any compelling evidence to support one type of needle biopsy over another. Occasionally, a core needle biopsy is not successful in obtaining the right type of tissue or sufficient amounts of tissue. In this case, a patient may require an open procedure when an incision is made. This is called an "excisional biopsy" and is not considered treatment, but is rather considered a diagnostic procedure. I have very low levels of enthusiasm for a procedure called a "fine needle aspirate." A fine needle aspirate involves just what it sounds like, the insertion of a very small needle into the abnormal area and because it doesn't get enough tissue, should not be used to rule out a cancer. In other words, if a physician is concerned that there may be a malignancy or pre-malignancy present, a fine needle aspirate is helpful only if it indeed shows cancer. If a fine needle aspirate is negative, the patient should proceed to a more adequate biopsy such as a core needle biopsy.
On December 19, 2007, our Ask-the-Expert Online Conference was called Updates from San Antonio 2007. Jennifer Griggs, M.D., M.P.H. answered your questions and shared the newest research presented at this year's San Antonio Breast Cancer Symposium.
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