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Other antidepressants for premenopausal women taking Tamoxifen?

Page last modified on: July 1, 2009
Question from Jenna: Are there other types of antidepressants (other than SSRIs and SNRIs) that a premenopausal patient can safely take with tamoxifen? Have they been extensively studied for interaction?
Answer —Nicholas Robert, M.D.: The drug is Effexor (chemical name: venlafaxine) and it’s been shown to be effective. It is used a lot to reduce hot flashes and it does not have a significant impact on tamoxifen. But Effexor is an antidepressant and can be used at higher doses to treat depression.

On Wednesday, June 24, 2009, our Ask-the-Expert Online Conference was called Updates from the ASCO Annual Meeting. Nick Robert, M.D. and Beth Baughman Dupree, M.D., F.A.C.S. answered your questions about the newest findings on risk, screening, treatment, and more.


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Nicholas Robert, M.D.Nicholas Robert, M.D. is a co-chair of the Breast Committee of the U.S. Oncology Research Network and also chairs the Cancer Committee and Research Committee of the Inova Fairfax Hospital's Cancer Center. 

Beth Baughman DuPree, M.D., F.A.C.S.Beth Baughman DuPree, M.D., F.A.C.S. the medical director of the Breast Health Program at Holy Redeemer Health System in Meadowbrook, PA.

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