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Additional treatment for HER2-positive after Herceptin?

Page last modified on: January 4, 2010
Question from Tigs: I was HER2+ (diagnosed in July of 06). I was wondering if there is anything out there on further treatment. I had a year of Herceptin but was hoping for some additional treatment.
Answer —Kathy Miller, M.D.: We know that treatment with a year of Herceptin (chemical name: trastuzumab) dramatically reduces the risk of recurrence so you should be feeling very good about your prognosis. But the fear of recurrence is always an issue. There is a study ongoing currently looking at adding treatment with an oral inhibitor of the HER2 factor after women have completed a year of Herceptin in the adjuvant setting. That study is still actively enrolling patients, so we have not seen any results from that study yet.

On Tuesday, December 15, 2009, our Ask-the-Expert Online Conference was called Updates from the 2009 San Antonio Breast Cancer Symposium. Kathy Miller, M.D. and Kristin Brill, M.D., F.A.C.S. answered your questions about the latest updates on breast cancer risk, screening techniques, treatment options, and more.


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Kathy D. Miller, M.D.Kathy D. Miller, M.D. is associate professor of medical oncology at Indiana University, and a Sheila D. Ward Scholar.

Kristin Brill, M.D., F.A.C.S. is a breast surgeon and clinical instructor at the Thomas Jefferson University Department of Surgery in Philadelphia, PA. She also maintains a practice in Cherry Hill, N.J. Dr. Brill is a fellow of the American College of Surgeons. In addition, she has published breast cancer research in medical journals such as Annals of Plastic Surgery and Cancer, and she has presented research at the American Society of Clinical Oncology.

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