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Clinical trials for IBC specifically?

Page last modified on: November 20, 2008
Question from Peggy: Are there any clinical trials going on that look at only inflammatory breast cancer?
Answers —Hope Rugo, M.D.: Yes, there are trials in the US looking at inflammatory breast cancer at a variety of different sites. Some information on those studies can be accessed at the NCI website mentioned earlier.

For women with inflammatory breast cancer that has metastasized or recurred, there are no clinical trials focusing on the history of inflammatory breast cancer. It falls under the category of women who have recurrent disease in general. We are recognizing that many women with inflammatory breast cancer have disease that is HER2-positive and there is interest in trying to treat the HER2- negative inflammatory breast cancer as well. We are designing a study with many collaborators including the University of North Carolina that will focus on women with hormone receptor negative and HER2-negative breast cancer and I suspect many of these women will have had inflammatory breast cancer.
Jennifer Armstrong, M.D.: The issue of treating inflammatory breast cancer distinctly touches upon an evolving understanding that we are gaining of breast cancer. In fact, we are beginning to understand that there are probably many different types of breast cancer. As we gain more insight into the different patterns of expression and behavior of these distinct entities, we hope to gain better insight into more effective treatment options. This will be particularly important in tumor types that behave aggressively.

On Wednesday, June 15, 2005 our Ask-the-Expert Online Conference was called Updates from the 2005 ASCO Annual Meeting. Hope Rugo, M.D. and moderator Jennifer Armstrong, M.D. answered your questions on the latest research advances presented at the 2005 American Society of Clinical Oncology meeting in Orlando, FL. 


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Hope S. Rugo, M.D.Hope S. Rugo, M.D. is a clinical professor of medicine in the division of hematology and oncology at the University of California San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center, where she directs the Breast Oncology Clinical Trials Program.

Jennifer Armstrong, M.D.Jennifer Armstrong, M.D. is a breast cancer oncologist at Paoli Hematology-Oncology Associates in Paoli, Pa., with a special interest in physicians' communication skills.

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