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Avastin with Aromasin for bone metastases?

Page last modified on: July 17, 2009
Question from Lin: Can Avastin be combined with Aromasin in a case of breast cancer with metastases to the bones?
Answer —Generosa Grana, M.D., F.A.C.P.: The only data that has been presented to date on Avastin is in combination with chemotherapy, in particular in combination with Taxol. Dr. Kathy Miller from Indiana University updated a trial that had been presented at the ASCO meeting in May, which compared Taxol alone to Avastin plus Taxol, with the Avastin given every two weeks intravenously, demonstrating a significant benefit in reducing risk of recurrence and improved survival when Avastin was added to Taxol.

Avastin is being studied in a variety of combinations—with chemotherapy, with Herceptin, with hormone therapy—but as of yet, there is no data on any of those combinations to show either effectiveness or toxicity.

On Wednesday, December 21, 2005, our Ask-the-Expert Online Conference was called Updates from San Antonio Breast Cancer Symposium 2005. Generosa Grana, M.D., F.A.C.P. and moderator Marisa Weiss, M.D. brought you the highlights of the 2005 Breast Cancer Symposium and answered your questions about the latest diagnostic and treatment options for breast cancer.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Generosa Grana, M.D., F.A.C.PGenerosa Grana, M.D., F.A.C.P. is the director of the Cooper Cancer Institute and heads the division of hematology/medical oncology at Cooper University Hospital.

Marisa Weiss, M.D. is a radiation oncologist specializing in breast cancer and the founder, president, and guiding force behind Breastcancer.org.

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