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Receptor-negative adjuvant treatment news?

Page last modified on: November 20, 2008
Question from Adrian: Any news regarding adjuvant treatment for receptor-negative breast cancer? Anything expected in near future?
Answer —Jennifer Griggs, M.D., M.P.H.: We've pointed out before on this website that most of the treatments with chemotherapy and most of the changes in how we give chemotherapy benefit people with estrogen-negative tumors than those who have had tumors that are estrogen-positive. That's just because of the biology of the tumor—chemotherapy works better when cells are dividing more rapidly, which in general negative-receptor tumors are. One of the things that we do in breast cancer care is move drugs or combinations of drugs from the treatment of metastatic disease into the adjuvant setting into people who do not have any evidence of disease following surgery. So we take drugs and combinations that are exciting in people where we can watch the disease respond and then start using those drugs or combinations in people who might fare very well in surgery alone. There are several very good clinical trials going on right now that are doing just that, and we are anxiously awaiting the results.

On Wednesday, June 21, 2006, our Ask-the-Expert Online Conference was called Updates from the 2006 ASCO Annual Meeting. Nicholas Robert, M.D. and moderator Jennifer Griggs, M.D., M.P.H. answered your questions about recent advances in breast cancer treatment, updates on breast cancer genetics, information on diet and risk of recurrence, and more.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Nicholas Robert, M.D.Nicholas Robert, M.D. is a co-chair of the Breast Committee of the U.S. Oncology Research Network and also chairs the Cancer Committee and Research Committee of the Inova Fairfax Hospital's Cancer Center. 

Jennifer Griggs, M.D., M.P.H.Jennifer Griggs, M.D., M.P.H. is a medical oncologist specializing in the treatment of breast cancer, with a a special interest in cancer survivorship, patient-physician communication, and quality of care for women with breast cancer.

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