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Herceptin and Tykerb effective for HER2+?

Page last modified on: November 20, 2008
Question from Heather: Have any studies been done comparing the effectiveness of Herceptin and Tykerb in the treatment of HER2-positive breast cancer, and if so, what are the results?
Answers —Nicholas Robert, M.D.: There has been a small study with pertuzumab and Herceptin. There was some benefit seen. Using other drugs like pertuzumab with other drugs like Tykerb is an area we're studying. I'm not aware of any particular studies at this time of that combination.
Generosa Grana, M.D., F.A.C.P.: Most of the data that's currently available on Tykerb is from patients who have failed prior Herceptin therapy.

On Wednesday, June 20, 2007, the Ask-the-Expert Online Conference was called Updates from the 2008 ASCO Annual Meeting. Generosa Grana, M.D., F.A.C.P. and moderator Nicholas Robert, M.D. answered your questions about the latest news on breast cancer screening, treatment, and side effects reported at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Generosa Grana, M.D., F.A.C.PGenerosa Grana, M.D., F.A.C.P. is the director of the Cooper Cancer Institute and heads the division of hematology/medical oncology at Cooper University Hospital.

Nicholas Robert, M.D.Nicholas Robert, M.D. is a co-chair of the Breast Committee of the U.S. Oncology Research Network and also chairs the Cancer Committee and Research Committee of the Inova Fairfax Hospital's Cancer Center. 

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