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Updates on treatment for triple-negative?

Page last modified on: November 20, 2008
Question from Twink: I was diagnosed in January with triple-negative breast cancer. I don't often read promising news regarding treatment of this type of cancer and would like to hear whether there's anything hopeful on the horizon for us triple-negative types. Also, I did read that carboplatin/cisplatin seems to show better survival results for triple-negative breast cancer; could the expert guests elaborate on that subject?
Answer —Nicholas Robert, M.D.: The category triple negative should be thought of as a group of tumors that are negative with our standard tests, but probably positive for other variables we don't know yet how to measure. There is work being done to understand the biology of so-called triple-negative tumors. In the meantime, there was a study showing the patients that are triple negative benefit from a regimen that contains weekly Taxol. There is also some work that is very preliminary, evaluating cisplatin (brand name: Platinol) and carboplatin (brand name: Paraplatin) in triple-negative breast cancer. At this point, it's too early to see whether these two agents will have a role in this cancer category.

On Wednesday, June 20, 2007, the Ask-the-Expert Online Conference was called Updates from the 2008 ASCO Annual Meeting. Generosa Grana, M.D., F.A.C.P. and moderator Nicholas Robert, M.D. answered your questions about the latest news on breast cancer screening, treatment, and side effects reported at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Generosa Grana, M.D., F.A.C.PGenerosa Grana, M.D., F.A.C.P. is the director of the Cooper Cancer Institute and heads the division of hematology/medical oncology at Cooper University Hospital.

Nicholas Robert, M.D.Nicholas Robert, M.D. is a co-chair of the Breast Committee of the U.S. Oncology Research Network and also chairs the Cancer Committee and Research Committee of the Inova Fairfax Hospital's Cancer Center. 

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