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Other bone metastasis medications?

Page last modified on: November 20, 2008
Question from Terese: Are there any new clinical trials or new targeted treatments for bone metastases that has just barely spread from breast cancer, other than Zometa and Faslodex?
Answer —Generosa Grana, M.D., F.A.C.P.: There is an interest, although no data as of yet, looking at agents such as Quadramet (chemical name: Samarium Sm-153 lexidronam) in this setting. This agent, which is a radioactive compound that is delivered intravenously and focuses on bone, has traditionally been used in women with bone metastases and pain. Currently, there are studies looking at this drug in addition to Zometa (chemical name: zoledronic acid) and we shall see where that research leads us.

On Wednesday, June 20, 2007, the Ask-the-Expert Online Conference was called Updates from the 2008 ASCO Annual MeetingGenerosa Grana, M.D., F.A.C.P. and moderator Nicholas Robert, M.D. answered your questions about the latest news on breast cancer screening, treatment, and side effects reported at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Generosa Grana, M.D., F.A.C.PGenerosa Grana, M.D., F.A.C.P. is the director of the Cooper Cancer Institute and heads the division of hematology/medical oncology at Cooper University Hospital.

Nicholas Robert, M.D.Nicholas Robert, M.D. is a co-chair of the Breast Committee of the U.S. Oncology Research Network and also chairs the Cancer Committee and Research Committee of the Inova Fairfax Hospital's Cancer Center. 

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