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Evista over Arimidex after lumpectomy and radiation?

Page last modified on: August 19, 2008

Question from Mare74: I am at high risk for cardiac disease. I am taking Arimidex after lumpectomy and radiation and am interested in your opinion on the new results on trials of Evista.: Answer —Generosa Grana, M.D., F.A.C.P.: While Evista (chemical name: raloxifene) is an interesting drug, its role is established only in the prevention setting, e.g., high-risk women using the drug to reduce their risk of breast cancer. There is very little data of Evista in metastatic breast cancer and none in either invasive disease or ductal carcinoma in situ. So for invasive breast cancer, the options remain tamoxifen or an aromatase inhibitor, such as Arimidex (chemical name: anastrozole), Femara (chemical name: letrozole), or Aromasin (chemical name: exemestane). There is no role in these patients for Evista.

On Wednesday, June 18, 2008 our Ask-the-Expert Online Conference was called Updates from the 2008 ASCO Annual Meeting. Generosa Grana, M.D., F.A.C.P. and Carol Kaplan, M.D. answered your questions about the latest research advances on screening, treatment, side effects, and more.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Generosa Grana, M.D., F.A.C.P. is the director of the Cooper Cancer Institute and heads the division of hematology/medical oncology at Cooper University Hospital.

Carol Kaplan, M.D. is an assistant professor of clinical medicine in the Rena Rowan Breast Center at the Hospital of the University of Pennsylvania. Her work revolves around the clinical care of breast cancer patients, as well as teaching medical students and house staff.

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