Home → Research News → Ask-the-Expert Conferences: Research News → June 2008: Updates from the 2008 ASCO Annual Meeting → PARP inhibitors to treat BRCA defects?

PARP inhibitors to treat BRCA defects?

Page last modified on: August 19, 2008

Question from PondsG: PARP inhibitors are being tested for efficacy against BRCA1 and 2 defects in breast and ovarian cancers. Is there any indication as to whether such treatments are likely to benefit both types? Is there any hope for a recurrence-preventive trial for those affected?: Answer —Carol Kaplan, M.D.: PARP inhibitors are drugs intended to target specifically the BRCA mutation carrier population. We happen to have an open clinical trial at the University of Pennsylvania that is currently enrolling breast cancer patients with metastatic disease. There has already been reported promising data for PARP inhibitor therapy for the treatment of ovarian cancer, fortunately. And preliminary clinical data in the breast cancer population suggests that this therapy could be worthwhile.

On Wednesday, June 18, 2008 our Ask-the-Expert Online Conference was called Updates from the 2008 ASCO Annual Meeting. Generosa Grana, M.D., F.A.C.P. and Carol Kaplan, M.D. answered your questions about the latest research advances on screening, treatment, side effects, and more.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

A production of LiveWorld, Inc.
Copyright 2008. All rights reserved.

Email Updates

Stay informed about current research, online events, and more.

Meet the Experts

Generosa Grana, M.D., F.A.C.P. is the director of the Cooper Cancer Institute and heads the division of hematology/medical oncology at Cooper University Hospital.

Carol Kaplan, M.D. is an assistant professor of clinical medicine in the Rena Rowan Breast Center at the Hospital of the University of Pennsylvania. Her work revolves around the clinical care of breast cancer patients, as well as teaching medical students and house staff.

Breastcancer.org is a non-profit organization dedicated to providing information and community to those touched by this disease. Learn more about our commitment to providing complete, accurate, and private breast cancer information.

Breastcancer.org 7 East Lancaster Avenue, 3rd Floor Ardmore, PA 19003

View Mobile Site