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Chemo-induced cardiomyopathy reversible?

Page last modified on: August 20, 2008

Question from Strnb: Have any studies been done that suggest chemo-induced cardiomyopathy is reversible?: Answer —Generosa Grana, M.D., F.A.C.P.: It depends on the type of chemotherapy that has led to the cardiomyopathy. There is good data that the cardiomyopathy related to Herceptin is very amenable to treatment, and may well be reversible in many but not all cases. The cardiotoxicity seen with anthracyclines tends to be somewhat more resistant. And there is data to suggest that it may be a bigger problem than we currently believe, particularly as women live longer and achieve older ages. So again, a lot of work is ongoing to try to predict who is at risk for cardiotoxicity with each of these specific agents and potentially to try to alter that risk.

On Wednesday, June 18, 2008 our Ask-the-Expert Online Conference was called Updates from the 2008 ASCO Annual Meeting. Generosa Grana, M.D., F.A.C.P. and Carol Kaplan, M.D. answered your questions about the latest research advances on screening, treatment, side effects, and more.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Generosa Grana, M.D., F.A.C.P. is the director of the Cooper Cancer Institute and heads the division of hematology/medical oncology at Cooper University Hospital.

Carol Kaplan, M.D. is an assistant professor of clinical medicine in the Rena Rowan Breast Center at the Hospital of the University of Pennsylvania. Her work revolves around the clinical care of breast cancer patients, as well as teaching medical students and house staff.

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