Clinical trials for gamma-secretase inhibitors and breast cancer stem cells?


Question from DJ: There was some exciting news about targeting breast cancer stem cells. My oncologist calls this the "holy grail." Any indication as to when trials may be open for "gamma-secretase inhibitors"?
Answers - Kathy D. Miller, M.D. The data on gamma-secretase inhibitors did look exciting, but it's important to remember this is early data in laboratory and animal models. It frequently takes several years to move those ideas into the clinic with the very first clinical trials. This is not an agent that I've had any experience with, so I don't know specifically how close they are to activating the first trial.

On Tuesday, December 15, 2009, our Ask-the-Expert Online Conference was called Updates from the 2009 San Antonio Breast Cancer Symposium. Kathy Miller, M.D. and Kristin Brill, M.D., F.A.C.S. answered your questions about the latest updates on breast cancer risk, screening techniques, treatment options, and more.

The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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