Latest on ER+ metastatic treatments?


Question from hawks: What are the latest treatments for metastatic breast cancer that is estrogen-receptor-positive?
Answers - Eric Winer, M.D. In general for women with estrogen-receptor-positive metastatic breast cancer, the therapy is hormonal therapy and the decision as to which hormonal therapy to select depends on what prior treatment the woman has had. We use hormonal therapy as long as possible because it tends to have fewer side effects and can be very effective. When hormonal therapy is no longer effective, we typically move to chemotherapy. Unfortunately, we are still in search of new targeted therapy to administer with hormonal therapy. But apart from drugs like Herceptin and lapatinib (brand name: Tykerb) for patients with estrogen-receptor-positive and HER2-positive breast cancer, we don't have others that are ready for prime time. There are many new therapies for estrogen-receptor-positive breast cancer that are under investigation.

On Wednesday, December 15, 2010, our Ask-the-Expert Online Conference was called Updates from the 2010 San Antonio Breast Cancer Symposium. Eric Winer, M.D. and Marisa Weiss, M.D. answered your questions about the latest updates on breast cancer risk, screening, and treatment in early and metastatic breast cancer.

The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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