Avastin with Abraxane for Stage IV treatment?


Question from NancyH: I was wondering what the latest is with using Avastin (along with Abraxane) for first line defense in Stage IV treatment. I'm concerned about the FDA decision and am wondering what the experts are saying. Thank you!
Answers - Eric Winer, M.D.

We don't know that Abraxane (chemical name: albumin-bound or nab-paclitaxel) plus Avastin (chemical name: bevacizumab) is better than Taxol (chemical name: paclitaxel) plus Avastin. There are studies underway to see if it is the same, better, or worse. The FDA will make a ruling on Avastin later this week. At present we know that Avastin is a drug that can help control cancer for a longer period of time when it is combined with chemotherapy, compared to chemotherapy alone. However, Avastin is not a drug that appears to extend the lives of women with metastatic breast cancer.

On Wednesday, December 15, 2010, our Ask-the-Expert Online Conference was called Updates from the 2010 San Antonio Breast Cancer Symposium. Eric Winer, M.D. and Marisa Weiss, M.D. answered your questions about the latest updates on breast cancer risk, screening, and treatment in early and metastatic breast cancer.

The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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