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Tamoxifen side effects. Suggestions?

Page last modified on: October 7, 2008
Question from Connie: I was diagnosed with ductal carcinoma in situ (DCIS), up-dated to pre-cancer small lesion. I had surgery and seven weeks of radiation. I was put on tamoxifen and could not handle side effects, so was told I could try Arimidex or just do all necessary follow-ups. I am 76 and not eager for any more side effects. I was on HRT for 26 years and am dealing with effects of stopping. Could you comment, please?
Answer —Beth DuPree, M.D., F.A.C.S.: With a non-invasive breast cancer at the age of 76 with appropriate surgical treatment and radiation therapy, it is within the realm of appropriate treatment to stop the tamoxifen therapy. Try the Arimidex (chemical name: anastrozole) or follow through with close clinical follow-ups, meaning breast exams every six months and follow up mammography.

On Wednesday, February 15, 2006, our Ask-the-Expert Online Conference was called Risk Reduction. Lynn C. Hartmann, M.D. and moderator Beth Baughman DuPree, M.D., F.A.C.S. answered your questions about a variety of topics such as screening with mammograms, MRIs, and ultrasounds; breast biopsies; lifestyle changes that make a difference; and making hard decisions about prophylactic surgeries.

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Meet the Experts

Lynn C. Hartmann, M.D.Lynn Hartmann, M.D. is a professor of oncology at the Mayo Clinic and associate director for education of the Mayo Clinic Cancer Center.

Beth Baughman DuPree, M.D., F.A.C.S.Beth Baughman DuPree, M.D., F.A.C.S. is a general surgeon. Her clinical practice is located at Holy Redeemer Hospital and St. Mary Medical Center.

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