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Gene mutations that have not been discovered?

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Ask-the-Expert Online Conference

Question from EHad: I am of Ashkenazi Jewish descent and surprised to learn that I am BRCA1/BRCA2 negative. My genetic counselor advises that my three daughters and one son are not at greater risk, and that I have no increased risk of ovarian cancer. How does my status impact my children? Are there other gene mutations for which we cannot test, or mutations not yet discovered?
Answers - Carol Cherry, M.S.N., R.N., A.P.R.N., B.C. Knowing which genes to test for is based on assessment of the complete family history of cancer. If there are other cancers other than breast in the family, there may be another syndrome for which testing is available. But this would only be more fully clarified if you seek counseling.

The Ask-the-Expert Online Conference Breast Cancer Risk and Your Family featured Terri McHugh, D.O., and Carol Cherry, M.S.N., R.N., A.P.R.N., B.C. answering your questions about genetics and breast cancer, and how your family could be affected.

Editor's Note: This conference took place in March 2008.

The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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