Tamoxifen to prevent HR+ recurrence?

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Question from AnnG: Is there any evidence to show that tamoxifen prevents the development of hormone-positive tumors at a later date in ER/PR-negative patients?
Answers - Kathy D. Miller, M.D. The short answer is no. In most women who have two separate primary breast cancers, those two breast cancers have the same ER status. So in most women whose initial breast cancer was ER-negative and who do develop a second breast cancer, that second breast cancer is also ER-negative. In women with ER-negative tumors, tamoxifen doesn't seem to decrease the risk of developing a second primary cancer.

The Ask-the-Expert Online Conference called Hormone-Receptor-Negative Breast Cancer featured Kathy D. Miller, M.D., Marisa Weiss, M.D., and moderator Jennifer Armstrong, M.D. answering your questions about a wide range of issues related to hormone-receptor-negative breast cancer.

Editor's Note: This conference took place in November 2005.

The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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