What counts as ER/PR-positive?

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Question from Myra: What percentage of cells must be positive for you to consider the breast cancer to be hormone-receptor-positive? My breast cancer was only 7% ER-positive, but was 61% PR-positive, so I am taking tamoxifen.
Answers - Jennifer Armstrong, M.D. Most people and most laboratories use a cutoff of 5-10% expression for positivity. As was mentioned earlier, expression of either progesterone or estrogen receptors is considered hormone-receptor-positive.

The Ask-the-Expert Online Conference called Hormone-Receptor-Negative Breast Cancer featured Kathy D. Miller, M.D., Marisa Weiss, M.D., and moderator Jennifer Armstrong, M.D. answering your questions about a wide range of issues related to hormone-receptor-negative breast cancer.

Editor's Note: This conference took place in November 2005.

The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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