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Arimidex for ER/PR-negatives?

Page last modified on: October 3, 2008
Question from Margaret: I was recently diagnosed with DCIS, estrogen- and progesterone-negative. As I am post-menopausal, my doctor has put me on Arimidex. Is that the latest protocol? I'm a bit concerned because I've been told I'm in early osteoporosis. Should I be concerned?
Answer —Kathy Miller, M.D.: Any time you're concerned about your doctor's recommendation is a good time to ask more questions and consider seeking a second opinion. You're right to be concerned about osteoporosis and increased bone loss that may come with Arimidex. With an estrogen-negative and progesterone-negative tumor, the benefit of taking Arimidex is probably very small, if any.

On Wednesday, November 19, 2005, our Ask-the-Expert Online Conference was called Hormone-Receptor-Negative Breast Cancer. Kathy D. Miller, M.D., Marisa Weiss, M.D., and moderator Jennifer Armstrong, M.D. answered your questions about a wide range of issues related to hormone-receptor-negative breast cancer.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Kathy D. Miller, M.D.Kathy D. Miller, M.D. is associate professor of medical oncology at Indiana University, and a Sheila D. Ward Scholar.

Marisa Weiss, M.D. is a radiation oncologist specializing in breast cancer and the founder, president, and guiding force behind Breastcancer.org.

Jennifer Armstrong, M.D.Jennifer Armstrong, M.D. is a breast cancer oncologist at Paoli Hematology-Oncology Associates in Paoli, Pa., with a special interest in physicians' communication skills.

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