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Why less research on ER/PR-negatives?

Page last modified on: October 6, 2008
Question from Steph: Why is there less research out there about hormone-receptor-negative breast cancer?
Answers —Jennifer Armstrong, M.D.: Simply because it's less common.
Kathy Miller, M.D.: I'm not sure there's less research about hormone-receptor-negative cancer, but you have to remember that we can't design a therapy to target a negative, or something that is missing in the cancer. So much of the research has focused on trying to identify what does drive the growth of those hormone-receptor-negative cancers, and then developing a therapy to target those factors. That research is just now developing into therapies that are in clinical trials.

On Wednesday, November 19, 2005, our Ask-the-Expert Online Conference was called Hormone-Receptor-Negative Breast CancerKathy D. Miller, M.D., Marisa Weiss, M.D., and moderator Jennifer Armstrong, M.D. answered your questions about a wide range of issues related to hormone-receptor-negative breast cancer.


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Kathy D. Miller, M.D.Kathy D. Miller, M.D. is associate professor of medical oncology at Indiana University, and a Sheila D. Ward Scholar.

Marisa Weiss, M.D. is a radiation oncologist specializing in breast cancer and the founder, president, and guiding force behind Breastcancer.org.

Jennifer Armstrong, M.D.Jennifer Armstrong, M.D. is a breast cancer oncologist at Paoli Hematology-Oncology Associates in Paoli, Pa., with a special interest in physicians' communication skills.

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