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How is extent of IBC determined?

Page last modified on: October 13, 2008
Question from Wayne: How does a surgeon determine the extent of the IBC after it has been visually eliminated by the chemotherapy? How do they determine the extent of the disease?
Answers —Jennifer Sabol, M.D., F.A.C.S.: When a mastectomy is performed, the surgeon will generally go in and remove the nipple and areola and as much of the overlying skin that has the inflammatory characteristics as they can. There are certain margins when the breast is removed, such as the collarbone, breastbone, and a line out of the arm that determine the edges of every mastectomy. The additional tissues that are removed under the arm, the axillary lymph nodes, is standard for both regular breast cancer and inflammatory breast cancer. If there are additional tissues involved outside the axillary, they will be removed as well. The final extent is really determined by the pathologist.
Gabriel Hortobagyi, M.D., F.A.C.P.: There is much interest, although no definitive proof, in using presurgical imaging such as MRI (magnetic resonance imaging) or PET (positron emission tomography) in an attempt to guide the surgeon in finding the extent. Additional research will be needed to validate that.

On Wednesday, October 18, 2006, our Ask-the-Expert Online Conference was called Inflammatory Breast Cancer. Gabriel Hortobagyi, M.D., Thomas Buchholz, M.D., and moderator Jennifer Sabol, M.D. answered your questions about inflammatory breast cancer, a rare but aggressive form of breast cancer.


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Gabriel N. Hortobagyi, M.D., F.A.C.P.Gabriel N. Hortobagyi, M.D., F.A.C.P. chairs the department of breast medical oncology and directs the Breast Cancer Research Program at the University of Texas M.D. Anderson Cancer Center, where he also serves as professor of medicine and holds the Nellie B. Connally Chair in Breast Cancer.

Thomas A. Buchholz, M.D.Thomas A. Buchholz, M.D. is professor of radiation oncology at The University of Texas M.D. Anderson Cancer Center. Dr. Buchholz' research includes the role of radiation treatment in preventing breast cancer recurrence and whether certain genes may be able to predict how breast cancer responds to treatment.

Jennifer Sabol, M.D., F.A.C.S.Jennifer Sabol, M.D., F.A.C.S. is a breast surgeon who directs the newly developed Breast Care Center at Lankenau Hospital in Wynnewood, Pa. Among her many interests, Dr. Sabol spearheads several research initiatives to advance the care for women with breast cancer and improve methods of breast cancer detection and treatment.

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