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Treatment for ulcerating skin metastases?

Page last modified on: October 13, 2008
Question from Hania: What treatment is suggested for ulcerating skin metastases?
Answers —Thomas Buchholz, M.D.: Radiation tends to be effective at helping ulcerations heal and helps frequently with pain associated with ulceration.
Gabriel Hortobagyi, M.D., F.A.C.P.: Depending on the timing of these ulcerated lesions in the overall treatment history, as well as the number and location of these lesions, one might select different treatments or treatment combinations. In the presence of a single or limited number of closely clustered ulcerated lesions, radiation might be an excellent choice. If there are multiple, especially widely spread lesions, then systemic therapy alone or in combination with selected local treatments might be a good choice too. Systemic treatments might be chemotherapy or hormonal therapy or something like Herceptin, depending on the type of tumor.

On Wednesday, October 18, 2006, our Ask-the-Expert Online Conference was called Inflammatory Breast Cancer. Gabriel Hortobagyi, M.D., Thomas Buchholz, M.D., and moderator Jennifer Sabol, M.D. answered your questions about inflammatory breast cancer, a rare but aggressive form of breast cancer.


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Gabriel N. Hortobagyi, M.D., F.A.C.P.Gabriel N. Hortobagyi, M.D., F.A.C.P. chairs the department of breast medical oncology and directs the Breast Cancer Research Program at the University of Texas M.D. Anderson Cancer Center, where he also serves as professor of medicine and holds the Nellie B. Connally Chair in Breast Cancer.

Thomas A. Buchholz, M.D.Thomas A. Buchholz, M.D. is professor of radiation oncology at The University of Texas M.D. Anderson Cancer Center. Dr. Buchholz' research includes the role of radiation treatment in preventing breast cancer recurrence and whether certain genes may be able to predict how breast cancer responds to treatment.

Jennifer Sabol, M.D., F.A.C.S.Jennifer Sabol, M.D., F.A.C.S. is a breast surgeon who directs the newly developed Breast Care Center at Lankenau Hospital in Wynnewood, Pa. Among her many interests, Dr. Sabol spearheads several research initiatives to advance the care for women with breast cancer and improve methods of breast cancer detection and treatment.

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