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Genetic testing for triple-negative?

Page last modified on: August 1, 2008
Question from Maija: So if triple-negative breast cancer is related to a defect in BRCA1, should members of the family be tested when the mother has triple-negative breast cancer?
Answer —Larry Norton, M.D.: It is a clue that BRCA1 may be involved. There is no substitute for expert genetic counseling if there is any suspicion of familial breast cancer. There are tools available online to help you estimate your chances of having a breast-cancer-related gene defect. But we have recently published that these tools are not extremely accurate. Hence, anybody with any suspicion should seek expert counseling to determine if testing is right for you.

On Wednesday, October 17, 2007 our Ask-the-Expert Online Conference was called Living with Metastatic Breast Cancer. Larry Norton, M.D. and moderator Marisa Weiss, M.D. answered your questions about managing day-to-day life with metastatic breast cancer.


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Larry Norton, M.D.Larry Norton, M.D. is deputy physician-in-chief and director of Breast Cancer Programs at Memorial Sloan-Kettering Cancer Center in New York City.

Marisa Weiss, M.D. is a radiation oncologist specializing in breast cancer and the founder, president, and guiding force behind Breastcancer.org.

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