Permanent infertility with chemo?

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Question from Pilar: With 4 cycles of Adriamycin (chemical name: doxorubicin) and Cytoxan (chemical name: cyclophosphamide), how likely is it that a 30-year-old woman would become permanently infertile?
Answers - Kutluk Oktay, M.D. The issue is that this type of chemotherapy results in loss of significant number of eggs from the woman's ovaries. While you may still menstruate after the treatment, your ovaries would behave like an older woman's ovaries. That means that you will have a smaller number of reproductive years to have children. Therefore, you should not waste time getting pregnant, and if you have difficulty you should seek advice from a specialist as soon as possible. If you're considering delaying childbearing further, you may also consider freezing your eggs if you're single or embryos if you have a partner because you will experience much earlier menopause than women who did not receive chemotherapy.

The Ask-the-Expert Online Conference called Fertility and Pregnancy featured Kutluk Oktay, M.D. and Leslie Schover, Ph.D. answering your questions about breast cancer treatments that can affect your fertility, options for preserving your fertility, being treated for breast cancer while pregnant, and more.

Editor's Note: This conference took place in September 2008.

The materials presented in these conferences do not necessarily reflect the views of A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Copyright 2010. All rights reserved.

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