Fatigue harms cancer patients' quality of life

Last Updated: 2006-12-21 13:00:14 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Among women diagnosed with breast cancer, fatigue is the symptom most strongly associated with a worse overall quality of life, German researchers report.

The influence of fatigue "by far" exceeded that of symptoms such as pain, nausea, and sleeping problems, Dr. Volker Arndt of the German Cancer Research Center in Heidelberg and colleagues found.

While cancer patients' symptoms are understood to have an impact on their quality of life, few researchers have attempted to separate out the individual effects of each symptom, they note in the journal Cancer.

To investigate, Arndt and colleagues surveyed 314 women one year after they were diagnosed with breast cancer, using a questionnaire that gauged both quality of life and levels of symptoms.

The most common symptoms the women reported were fatigue, sleeping problems, pain, and symptoms involving the arms, the researchers found.

Fatigue was the most important factor determining a woman's overall quality of life, the researchers found, accounting for 30 percent to 50 percent of variability in quality of life scores.

Little is known about the causes of fatigue in cancer patients, and there is a "profound communication gap" between doctors and patients regarding cancer-related fatigue, Arndt and colleagues write.

Suggested treatments include "mild physical exercise, sleep hygiene and attention-restoring activities," they add, and while therapy with stimulant drugs, transfusion of red blood cells, or treatment with red blood cell-boosting erythropoietin have all been suggested as well, there is little evidence on their effectiveness.

"These findings suggest that efforts to reduce specifically the burden of fatigue may be very promising approaches to enhance quality of life in breast cancer survivors," Arndt and colleagues conclude.

SOURCE: Cancer, November 15, 2006.

 
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What breastcancer.org says about this article…

Fatigue harms cancer patients' quality of life

Fatigue is probably the one symptom shared by nearly all women being treated for breast cancer. The study reviewed here shows that fatigue affects the quality of life of women with breast cancer more than any other symptom.

There are many causes of fatigue and one cause can affect all the others. Sometimes fatigue is related to your body's reaction to the cancer. The therapies used to treat breast cancer also can cause fatigue. The emotional roller coaster of breast cancer diagnosis and treatment just adds to the other causes of fatigue.

If you're experiencing fatigue related to breast cancer, you know how real it is and how much it can affect your quality of life. Still, there are a number of things you can do to minimize fatigue and its impact on your life. Here are just a few:

  • Get regular, moderate exercise. It may seem strange, but moderate, regular exercise—such as a daily walk or swim—often minimizes fatigue.
  • Eat well and keep well-hydrated. More than ever, your body needs healthy fuel and fluids to heal and restore itself.
  • Take a nap if you feel like it.
  • Get a good night's sleep.
  • Ask your doctor about medical causes for your fatigue and what you can do to treat them. Anemia is known to cause fatigue and can be treated with medicine.

For much more information about fatigue, its causes, and the things you can do to minimize it, visit the Breastcancer.org Fatigue section.

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