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Does anything counteract with Arimidex?

Page last modified on: October 14, 2008
Question from JanM: Are there any vitamins, herbal supplements or foods that counteract with Arimidex? I know grapefruit interfered with tamoxifen.
Answer —Gary Deng, M.D., Ph.D.: Arimidex is in a class of drugs called aromatase inhibitors. Aromatase is an enzyme that is closely related to drug-metabolizing P450 enzyme system in our body. We know several herbs interact with P450 enzyme, the most prominent one being St. John's wort. Therefore, people should avoid herbs that are known to interact with the P450 system.

On Wednesday, July 18, 2007, our Ask-the-Expert Online Conference was called Vitamins and Herbal Supplements. Gary Deng, M.D., Ph.D. and moderator Beth Baughman DuPree, M.D., F.A.C.S. answered your questions about how to safely and sensibly incorporate vitamins and supplements into your diet.


The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Gary Deng, M.D., Ph.D. is an internist and researcher with the Integrative Medicine Service at Memorial Sloan-Kettering Cancer Center. He is a principal investigator or co-principal investigator in several NIH-funded research projects in the Integrative Medicine Service.

Beth Baughman DuPree, M.D., F.A.C.S.Beth Baughman DuPree, M.D., F.A.C.S. the medical director of the Breast Health Program at Holy Redeemer Health System in Meadowbrook, PA.

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