Skip to content

More chemo after 6x CMF?

Page last modified on: September 19, 2008
Question from Tonio: Hello from Spain. My wife, 37 years old, was diagnosed with invasive ductal carcinoma (T1N0M0), 2 cm., ER+, PR+, c-erbB-2- (HER-2/neu negative). She has been treated with 6 x CMF, finishing last week, but we believe that it is not the optimum treatment. Would it be possible to add any anthracycline or taxane regimen now?
Answer —Jennifer Griggs, M.D., M.P.H.: Actually, the treatment you've outlined is excellent. Although very large studies suggest a possible benefit to regimens that contain an anthracycline, there are no features of your wife's tumor that make me think this class of drug would be necessary. I am assuming that she will also go on a hormonal-acting agent, such as tamoxifen.

Tumors that have the c-erbB-2- (in other words, are negative for HER-2/neu) can get a good response to CMF chemotherapy as well as to Adriamycin chemotherapy, but tumors that are HER-2 positive may respond better to an Adriamycin-based or a taxane-based chemotherapy.

On Wednesday, February 18, 2004, our Ask-the-Expert Online Conference was called Chemotherapy Updates. Jennifer Griggs, M.D., M.P.H. and Marisa Weiss, M.D. answered your questions about advances in chemotherapy treatment: different types of drugs and regimens, how to reduce or eliminate unpleasant side effects, and more.

The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

A production of LiveWorld, Inc.
Copyright 2008. All rights reserved.

wellness_dvd_promo

Email Updates

Stay informed about current research, online events, and more.

Please leave this field empty

Meet the Experts

Jennifer Griggs, M.D., M.P.H.Jennifer Griggs, M.D., M.P.H. is a medical oncologist specializing in the treatment of breast cancer, with a a special interest in cancer survivorship, patient-physician communication, and quality of care for women with breast cancer.

Marisa Weiss, M.D. is a radiation oncologist specializing in breast cancer and the founder, president, and guiding force behind Breastcancer.org.

Back to top

Breastcancer.org 7 East Lancaster Avenue, 3rd Floor Ardmore, PA 19003

Learn more about our commitment to your privacy

© 2009 Breastcancer.org - All rights reserved.

Breastcancer.org is a non-profit organization dedicated to providing information and community to those touched by this disease. Learn more about our commitment to providing complete, accurate, and private breast cancer information.