Difference between Adriamycin and Cytoxan?

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Question from Sprph: What is the difference in mechanism of action of Adriamycin vs. Cytoxan? Both act on cell-wall replication, so why both?
Answers - Jennifer Griggs, M.D., M.P.H. Both drugs actually work on DNA, rather than cell walls, but the drugs actually work in different ways. For example, Adriamycin has several ways in which it works. There is no reason to think that receiving both drugs is redundant.

The Ask-the-Expert Online Conference called Chemotherapy Updates featured Jennifer Griggs, M.D., M.P.H. and Marisa Weiss, M.D. answering your questions about advances in chemotherapy treatment: different types of drugs and regimens, how to reduce or eliminate unpleasant side effects, and more.

Editor's Note: This conference took place in February 2002.

The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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