Hormonal therapy for ER-negative, PR-positive?

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Question from Katie: Which hormonal therapies are effective with estrogen-negative, progesterone-positive breast cancer?
Answers - Sandra F. Schnall, M.D. Most of them are as effective in either situation. I don't tend to recommend one hormonal therapy vs. another based on that alone.
Marisa Weiss, M.D. Most oncologists consider a patient's cancer to be hormone-receptor-positive if either or both the estrogen and progesterone receptors are positive (meaning present).
Sandra F. Schnall, M.D. We do quantify the percentage of them being present, so that less than 5% to 10% may not be strongly positive. If just the progesterone was 5% positive with the estrogen receptor being negative, it may not equate to a strong hormone response, but the treatment would be the same.

The Ask-the-Expert Online Conference called Hormonal Therapy Updates featured Sandra Schnall, M.D. and Marisa Weiss, M.D. answering your questions about hormonal therapies and answered questions about which ones work best in different situations, how they might fit into your treatment sequence, how to deal with side effects, and more.

Editor's Note: This conference took place in April 2004.

The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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