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Femara even when not tested for receptors?

Page last modified on: October 13, 2008
Question from NancieR: I had DCIS and radiation therapy. I'm on Femara, which makes my joints ache and gives me additional trouble sleeping. Because they did not test the DCIS for whether it was hormone positive (said it wasn't done in such cases), I question the value of taking Femara. I feel 10 years older in the year I've taken it.
Answer —Patricia Ganz, M.D.: Please ask your doctor to have your tissue tested for estrogen and progesterone receptors. This is a standard assay that can be done on your tissue. If you are hormone-receptor-positive, we would recommend tamoxifen, which is the standard therapy in this situation. You might tolerate that better than the Femara. But rather than having me give you specific advice, you might wish to seek a second opinion to review your case in detail.

On Wednesday, August 15, 2007, the Ask-the-Expert Online Conference was called Managing Ongoing MedicationsPatricia Ganz, M.D. and moderator Lillie Shockney, R.N., B.S., M.A.S. answered your questions about staying on track with breast cancer medications you have to take on a regular basis.


The materials presented in these conferences do not necessarily reflect the views of breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.

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Meet the Experts

Patricia A. Ganz, M.D.Patricia A. Ganz, M.D. is a medical oncologist and a professor in the schools of medicine and public health at UCLA, and is director of the division of cancer prevention and control research at the Jonsson Comprehensive Cancer Center there.

Lillie Shockney, RN., BS., M.A.S.Lillie Shockney, R.N., B.S., M.A.S. is the administrative director of the Johns Hopkins Avon Foundation Breast Center.

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