Stage IIIA and Operable IIIC

Tumor greater than 5 cm with lymph nodes involved (IIIA) OR
Tumor less than 5 cm and lymph nodes under the arm involved and clumped together (IIIA) OR
Any size tumor with spread to more than 10 lymph nodes in or near the breast and/or lymph nodes near the neck or under the collarbone (operable IIIC)

Modified radical mastectomy followed by radiation

OR

Lumpectomy plus radiation following chemotherapy to shrink a large single cancer

Axillary lymph nodes removed by traditional approach

AND

Possible radiation to supraclavicular and/or internal mammary lymph nodes

Almost always recommended

Used for people with hormone-receptor-positive cancer

May be used for people with cancers that have certain characteristics (for example, cancers with too many HER2 protein receptors)

Does not apply