The large study (more than 150,000 patient histories were reviewed) reviewed here found that more women chose to have both breasts removed -- even though cancer had been found in only one breast -- between 1998 and 2003. Surgery to remove both breasts is called double or bilateral mastectomy.
The study didn't pinpoint why more women are choosing double mastectomy. But it's likely the women chose this surgery because they were concerned about developing breast cancer in the other breast. Being diagnosed with breast cancer increases the risk of developing a new, different breast cancer in the future.
For women who don't have an abnormal BRCA1 or BRCA2 gene, the risk of developing a new breast cancer in the other breast is about 1% a year. After 10 years, this risk is about 10%. For women who have an abnormal BRCA1 or BRCA2 gene, the risk of developing a new breast cancer in the other breast is higher. Their risk can be 3 to 4% per year (30% to 40% over 10 years).
Every woman diagnosed with breast cancer has to ask herself this question: for me, how much risk is enough to make a decision to remove a healthy breast after cancer has affected my other breast?
Because each woman's situation is unique, every woman will have a different answer to the question.
Double mastectomy is more common among younger women and among women who have been diagnosed twice with breast cancer. Younger women have more time ahead of them to possibly develop a second breast cancer. Women diagnosed with breast cancer more than once are understandably concerned about being diagnosed yet again, even if they don't have an abnormal BRCA1 or BRCA2 gene.
If you're considering double mastectomy to reduce future risk, here are some things to consider:
Talk to your medical team about all your options and make your decisions based on the best information available for YOU and your unique situation.
NEW YORK (Reuters Health) - From 1998 through 2003, the rate of double mastectomies among women in the United States who had cancer diagnosed in only one breast more than doubled, according to a report in the Journal of Clinical Oncology.
"Many surgeons had noticed that more women were requesting double mastectomy for treatment of the cancer in only one breast. So, we weren't surprised by the overall trend, but we were very surprised by the magnitude," lead author Dr. Todd M. Tuttle said in an interview with Reuters Health.
What is driving this trend will require further studies, added Tuttle, from the University of Minnesota in Minneapolis. In the meantime, he advised, it is critical that physicians be aware and inform their patients that "although there may be sound reasons for undergoing double mastectomy (avoidance of future mammograms and preventing a new cancer), the procedure does not improve breast cancer survival."
The new study involved an analysis of data for 152,755 women who were diagnosed with cancer in one breast between 1998 and 2003 and entered in the Surveillance, Epidemiology, and End Results (SEER), the US National Cancer Institutes' database.
Overall, 4,969 patients elected to undergo preventative mastectomy in the other breast. The rates of the operation were 3.3 percent among women who had any surgery, including those who underwent single mastectomy or only had their tumor removed, and 7.7 percent among mastectomy patients.
The overall rate of double mastectomy - that included removal of an unaffected breast climbed from 1.8 percent in 1998 to 4.5 percent in 2003, the report indicates. Among mastectomy patients, the rate rose from 4.2 percent to 11.0 percent. These trends were noted for patients at any cancer stage and were still apparent at the end of the study period.
Characteristics of the women who underwent double mastectomy included younger patient age, non-Hispanic white race, lobular breast cancer type, and a prior cancer diagnosis, the researchers found. Large tumor size was associated with an increase in the overall rate of the procedure, but with a decrease in the rate among mastectomy patients.
"The main unanswered question from this research is: why are more women choosing to undergo double mastectomy?" Tuttle said. "For our next research project, we will interview breast cancer patients before and after surgery to determine what factors influenced their surgical decisions. We will also interview patients' surgeons to determine their advice."
SOURCE: Journal of Clinical Oncology, October 22, 2007 online.
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