Ibrance

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Brand name: Ibrance

Chemical name: Palbociclib

Class: Cyclin-dependent kinase (CDK) 4/6 inhibitor. Kisqali and Verzenio are other CDK4/6 inhibitors used to treat breast cancer.

How it works: A kinase is a type of protein in the body that helps control cell division. Ibrance works by inhibiting the kinase and stopping cancer cells from dividing and growing.

Uses: Ibrance is used in combination with an aromatase inhibitor to treat advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer that hasn’t been treated with hormonal therapy before in postmenopausal women and men. Arimidex (chemical name: anastrozole), Aromasin (chemical name: exemestane), and Femara (chemical name: letrozole) are aromatase inhibitors.

Ibrance also is approved to be used in combination with Faslodex (chemical name: fulvestrant) to treat advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer that has grown after being treated with hormonal therapy in postmenopausal women and men.

How it’s given: Ibrance is a pill taken by mouth.

Side effects:

Read more about Ibrance.


References

  1. Ibrance (palbociclib) prescribing information. Pfizer. New York, NY. 2018. Available at http://labeling.pfizer.com/ShowLabeling.aspx?id=2191.

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