Brand name: Ibrance
Chemical name: Palbociclib
How it works: A kinase is a type of protein in the body that helps control cell division. Ibrance works by inhibiting the kinase and stopping cancer cells from dividing and growing.
Uses: Ibrance is used in combination with an aromatase inhibitor to treat advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer that hasn’t been treated with hormonal therapy before in postmenopausal women. Arimidex (chemical name: anastrozole), Aromasin (chemical name: exemestane), and Femara (chemical name: letrozole) are aromatase inhibitors.
Ibrance also is approved to be used in combination with Faslodex (chemical name: fulvestrant) to treat advanced-stage or metastatic, hormone-receptor-positive, HER2-negative breast cancer that has grown after being treated with hormonal therapy in postmenopausal women.
How it’s given: Ibrance is a pill taken by mouth.
- anemia (low red blood cell count)
- mouth sores
- hair thinning or loss
- decreased appetite
- neutropenia (low white blood cell count)
- blood clots
Read more about Ibrance.
- Ibrance (palbociclib) prescribing information. Pfizer. New York, NY. 2018. Available at http://labeling.pfizer.com/ShowLabeling.aspx?id=2191.