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Brand name: Nerlynx

Chemical name: neratinib

Class: Irreversible pan-HER (human epidermal receptor) inhibitor targeted therapy. Herceptin, Herzuma, Kanjinti, Ogivri, Ontruzant, Perjeta, Trazimera, and Tykerb are other HER2 inhibitors.

How it works: HER inhibitors work against HER2-positive breast cancers by blocking the ability of the cancer cells to receive chemical signals that tell the cells to grow.

Uses: Nerlynx is used to treat early-stage, HER2-positive breast cancer for an extended period of time after surgery (doctors call this extended adjuvant therapy). You take Nerlynx within 2 years after you’ve had surgery and completed a chemotherapy regimen that included Herceptin.

Nerlynx was the first medicine to be approved specially for extended adjuvant therapy for early-stage, HER2-positive disease.

How it’s given: Nerlynx is a pill taken by mouth. The recommended dose of Nerlynx is 240 mg (6 tablets) once per day with food for 1 year.

Side effects:

Read more about Nerlynx.

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