Brand name: Nerlynx
Chemical name: neratinib
How it works: HER inhibitors work against HER2-positive breast cancers by blocking the ability of the cancer cells to receive chemical signals that tell the cells to grow.
Uses: Nerlynx is used to treat early-stage, HER2-positive breast cancer for an extended period of time after surgery (doctors call this extended adjuvant therapy). You take Nerlynx within 2 years after you’ve had surgery and completed a chemotherapy regimen that included Herceptin.
Nerlynx was the first medicine to be approved specially for extended adjuvant therapy for early-stage, HER2-positive disease.
How it’s given: Nerlynx is a pill taken by mouth. The recommended dose of Nerlynx is 240 mg (6 tablets) once per day with food for 1 year.