Brand name: Tukysa
Chemical name: Tucatinib
Class: Tyrosine kinase inhibitor
How it works: Tyrosine kinases are enzymes that help control how cells grow and divide, among other functions. If the enzyme is too active or if a cell has too much of the enzyme, it can make cells grow uncontrollably. Tukysa blocks a specific area of the HER2 gene in cancer cells, which stops the cells from growing and spreading.
Uses: Tukysa is used in combination with Herceptin (chemical name: trastuzumab) and Xeloda (chemical name: capecitabine) to treat metastatic HER2-positive breast cancer or locally advanced HER2-positive disease that can’t be completely removed with surgery, after the cancer has been treated with at least one anti-HER2 medicine.
How it’s given: Tukysa is a pill taken by mouth.
- hand-foot syndrome
- liver problems
- mouth sores
- decreased appetite
- abdominal pain
Read more about Tukysa.
- Tukysa (tucatinib) prescribing information. Seattle Genetics, Inc. Bothell, WA. 2020. Available at: https://seagendocs.com/TUKYSA_Full_Ltr_Master.pdf (PDF)
Can we help guide you?
Create a profile for better recommendations
Tamoxifen (Brand Names: Nolvadex, Soltamox)
Tamoxifen is the oldest and most-prescribed selective estrogen receptor modulator (SERM)....
Breast Cancer Stages
The stage of a breast cancer is determined by the cancer’s characteristics, such as how large it...
Cancer Survivors Overestimate Quality of Their Diets
Most people who have been diagnosed with cancer think they eat a healthy diet, but a study found...