Kisqali can be used to treat both premenopausal and postmenopausal women. So it’s important to know that women who are pregnant or planning to get pregnant should not take Kisqali. Kisqali can harm the developing fetus. It’s important that you don’t get pregnant while taking Kisqali; if there is any chance you can become pregnant, you must use effective birth control while you’re taking Kisqali and for at least 3 weeks after your last dose.
Also, women who are breastfeeding or plan to breastfeed shouldn’t take Kisqali. Together, you and your doctor will decide if you should take Kisqali or breastfeed.
The most common side effects of Kisqali are:
- hair loss
- back pain
- low white blood cell counts
Kisqali also may cause serious side effects, including:
Heart problems known as QT prolongation: This condition can cause an abnormal heartbeat and can be fatal. Tell your doctor right away if you have a change in heartbeat, including a fast or irregular heartbeat, or if you feel dizzy or like you might faint.
Liver problems: Tell your doctor right away if you have any of the following signs of liver problems:
- yellowing of the skin or the whites of the eyes
- dark or brown urine
- feeling very tired
- loss of appetite
- pain on the upper right side of the abdomen
- bleeding or bruising more easily than normal
Neutropenia (low white blood cell count): Low white blood cell counts are a common side effect of Kisqali. Still, some women’s white blood cell counts may drop so low that they have to decrease the dose of Kisqali or stop treatment. Your doctor will check your white blood cell count before and during treatment with Kisqali.
Because Kisqali is given with an aromatase inhibitor and a luteinizing hormone-releasing hormone agonist, such as Zoladex (chemical name: goserelin), or Faslodex (chemical name: fulvestrant), you also may have aromatase inhibitor, Faslodex, or Zoladex side effects. Common side effects of aromatase inhibitors are joint stiffness and bone/joint pain. Common side effects of Faslodex are hot flashes, nausea, and vomiting. Common side effects of Zoladex are hot flashes, mood swings, and loss of libido.