Kisqali is prescribed with either tamoxifen or an aromatase inhibitor. All three medicines are pills taken by mouth.
You take Kisqali and the aromatase inhibitor on a 28-day cycle:
- for 21 days, you take the Kisqali and aromatase inhibitor or tamoxifen pills at the same time each day, with or without food
- then for 7 days, you take only the aromatase inhibitor or tamoxifen
There are certain medicines, supplements, and foods you should not take or eat if you are taking Kisqali.
You should not take a type of medicine called a CYP3A inhibitor because it increases the effects of Kisqali. This class of medicines includes antifungal medicines such as Onmel (chemical name: itraconazole) and Biaxin (chemical name: clarithromycin), as well as antiretroviral drugs used to treat HIV such as Kaletra (chemical name: lopinavir and ritonavir).
You should not take a type of medicine called a CYP3A inducer because it decreases the effects of Kisqali. This class of medicines includes Rifamate (chemical name: rifampin), an antibiotic used to treat tuberculosis, and Carbatrol (chemical name: carbamazepine), which is used to control certain types of seizures in people with epilepsy.
You should not take Kisqali with medicines used to treat improper beating of the heart, whether too fast or too slow. These medicines include Cordarone (chemical name: amiodarone), Norpace (chemical name: disopyramide), procainamide, Quinaglute (chemical name: quinidine), and Betapace (chemical name: sotalol).
You should not eat grapefruit or pomegranate or drink grapefruit juice or pomegranate juice because they can increase the effects of Kisqali.
If your doctor prescribes Kisqali and you have problems getting it covered by insurance or you don’t have insurance, the Kisqali patient support program may be able to help you. To talk to a Kisqali patient support representative, call 1-800-282-7630.