Verzenio can be used:
- In combination with Faslodex (chemical name: fulvestrant) to treat women diagnosed with hormone-receptor-positive, HER2-negative metastatic or advanced-stage breast cancer if the cancer progressed after hormonal therapy treatment.
- Alone — called monotherapy by doctors — to treat women and men diagnosed with hormone-receptor-positive, HER2-negative metastatic or advanced-stage breast cancer if the cancer progressed after hormonal therapy treatment and earlier chemotherapy for metastatic disease.
- In combination with an aromatase inhibitor to treat postmenopausal women diagnosed with metastatic or advanced-stage hormone-receptor-positive, HER2-negative breast cancer that has not been treated with hormonal therapy yet.
Verzenio is a pill taken by mouth. The recommended starting doses of Verzenio are 150 mg twice per day in combination with Faslodex or an aromatase inhibitor, or 200 mg twice per day used alone.
There are certain medicines, supplements, and foods you should not take or eat if you are taking Verzenio.
You should not take a type of medicine called a strong CYP3A inhibitor because it increases the effects of Verzenio. This class of medicines includes antifungal medicines such as Nizoral (chemical name: ketoconazole).
You should not take a type of medicine called a strong CYP3A inducer because it decreases the effects of Verzenio. This class of medicines includes Rifamate (chemical name: rifampin), an antibiotic used to treat tuberculosis.
You should not eat grapefruit or drink grapefruit juice because they can increase the effects of Verzenio.
Pregnant women should not get targeted therapies such as Verzenio. The little research that has been done suggests that targeted therapies are not safe during pregnancy. Visit the Treatment for Breast Cancer During Pregnancy page for more information.
If your doctor prescribes Verzenio and you have problems getting it covered by insurance or have problems paying for the treatment, Eli Lilly and Company, the company that makes Verzenio, may be able to help you.
In the United States, Lilly has ways to help people understand their insurance benefits and financial assistance options:
- Lilly offers a savings card program for eligible, commercially-insured patients to assist with out-of-pocket costs. The savings card program provides first 3 months of Verzenio for free, then the patient pays no more than $10 per month. The patient can use the savings card for up to 12 months ($25,000 annual cap). For more information, please visit www.verzenio.com.
- Through the Verzenio Continuous Care Program, patients can enroll in the Lilly Benefits Investigation support program that helps patients navigate their insurance benefits to learn how they may be able to pay the lowest out-of-pocket cost. To learn more about the support available, visit verzenio.com or call 1-844-VERZENIO (1-844-837-9364).
- Lilly also donates medicines to the Lilly Cares Foundation, a separate nonprofit organization, that provides Lilly medicines to qualifying patients at no cost. Learn more about Lilly Cares at www.lillycares.com or by calling 1-800-545-6962.