Veozah (fezolinetant) for Hot Flashes
Updated on September 27, 2025
If you’re experiencing moderate to severe hot flashes from breast cancer treatments or menopause, you may want to talk with your doctor about getting a prescription for Veozah. Veozah is one of several hormone-free medications used to treat hot flashes.
See Veozah prescribing information.
How Veozah works
Hot flashes and night sweats (also called vasomotor symptoms) are caused by changes in how the brain regulates body temperature. When estrogen levels drop, a chemical called neurokinin B (NKB) pushes cells in the brain’s temperature control center into overdrive. This can cause vasomotor symptoms, making you feel hot and sweaty.
Veozah works by blocking NKB from overactivating the brain cells involved in temperature control.
What to expect with Veozah
Veozah is a 45-milligram tablet you take by mouth once daily. You can take the tablets with or without food, but should avoid cutting, crushing, or chewing them.
Take the tablet at about the same time each day. If you miss a dose, take it as soon as possible, unless it’s under 12 hours until your next scheduled dose. If that happens, just resume your regular schedule the next day.
Veozah side effects
The most common side effects of Veozah include:
Veozah can also cause serious liver problems. Before you start taking the medicine, your healthcare team will give you a blood test to check your liver.
If your doctor clears you to start taking Veozah, you’ll get monthly blood tests for the first three months, then at six and nine months. If anything about your blood tests concerns your doctor, they’ll have you stop taking it.
Stop taking Veozah and call your doctor if you experience the following symptoms:
extreme tiredness
decreased appetite
nausea
vomiting
itching
yellowing of the eyes or skin
pale stool
dark urine
Do not take Veozah if you have cirrhosis, severe kidney problems, or kidney failure.
Veozah is a relatively new medication, so there is currently no data on the use of Veozah in pregnant or nursing women. Talk to your doctor if you’re pregnant, trying to get pregnant, or breastfeeding before you take Veozah.
Drug interactions
Certain medicines, called CYP1A2 inhibitors, can slow down the breakdown of Veozah, causing it to accumulate in the body and increase the risk of side effects.
CYP1A2 inhibitors include:
fluvoxamine
ciprofloxacin
enoxacin
Real patient reviews
Members of our community discuss their experiences with Veozah in the community forum. Here are some of their comments. Remember, it's very important to talk to your doctor about any side effects you're having and ask about ways to manage them.
“I started taking Veozah about a month ago, and it is working very well. I had been on ovarian suppression plus AI [aromatase inhibitor] and, in the past, took Effexor, but I find Veozah to be much more effective. For what it's worth! I did have to jump through a few hoops to get it covered by insurance, but ultimately it was covered.” — smiling_brenda
“I did have horrible hot flashes and night sweats [on anastrozole]. I managed with Veozah samples from my general doctor for a few weeks, and they finally subsided.” — jillmarie
Join the discussion in the Breastcancer.org community.
Paying for Veozah
The cost of Veozah may vary. The price you’ll pay depends on your health insurance provider and plan, where you live, and the pharmacy you use.
Note: Your insurance company may require you to get prior authorization before covering Veozah.
If you have trouble paying for Veozah, ask your pharmacist or care team about financial assistance programs that may be able to help.
Learn more about financial assistance and medicine cost-lowering tips.