Join Us


Save as Favorite
Sign in to receive recommendations (Learn more)

Brand name: Trodelvy

Chemical name: Sacituzumab govitecan-hziy

Class: Antibody-drug conjugate immune targeted therapy. Trodelvy is made up of:

  • sacituzumab, a type of protein called a monoclonal antibody, that targets the Trop-2 protein; the Trop-2 protein is found in more than 90% of triple-negative breast cancers
  • SN-38, a topoisomerase I inhibitor chemotherapy; topoisomerase I inhibitors work by interfering with the cancer cells’ ability to replicate
  • a compound that links the sacituzumab to the SN-38

The linking compound attaches (conjugates) the monoclonal antibody sacituzumab to the SN-38 chemotherapy.

Uses: Trodelvy is used to treat adults diagnosed with metastatic triple-negative breast cancer who have received at least two previous treatments for metastatic disease.

How it’s given: Trodelvy is given intravenously, which means the medicine is delivered directly into your bloodstream through an IV or port.

Side effects:

Read more about Trodelvy.


  1. Trodelvy (sacituzumab govitecan-hziy) prescribing information. Immunomedics, Morris Plains, NJ. 2020. Available at: (PDF)

Was this article helpful? Yes / No
Rn icon

Can we help guide you?

Create a profile for better recommendations

How does this work? Learn more
Are these recommendations helpful? Take a quick survey

2021eg sidebarad v01
Back to Top