comscoreFezolinetant: A Non-Hormonal Treatment for Hot Flashes

Fezolinetant: A Non-Hormonal Treatment for Hot Flashes

Genevieve Neal-Perry, MD, PhD, discusses her research on fezolinetant as a treatment for hot flashes.
Jul 22, 2022

If you’ve been diagnosed with breast cancer before menopause, some of your treatments, including chemotherapy and hormonal therapy, can bring on menopause earlier and more abruptly than expected, causing hot flashes and night sweats. For some women, these symptoms can be severe and dramatically affect their quality of life. 

In search of relief, some women consider hormone replacement therapy (HRT). But because HRT contains hormones — estrogen or a combination of estrogen and progesterone — which can make breast cells grow, it is not recommended for women who have been diagnosed with breast cancer.

Listen to the podcast to hear Dr. Neal-Perry explain:

  • how fezolinetant works to ease hot flashes

  • fezolinetant side effects

  • why the results of her work on the SKYLIGHT 2 study are so exciting for women with a history of breast cancer

About the guest
Genevieve Neal-Perry headshot
Genevieve Neal-Perry, MD, PhD

Dr. Genevieve Neal-Perry is the Robert A. Ross Distinguished Professor and chair of the Department of Obstetrics and Gynecology at the University of North Carolina School of Medicine. Her research program focuses on menopause and its symptoms and the impact of nutrition on reproductive and fertility outcomes.

— Last updated on July 22, 2022, 6:39 PM

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