Stage IIIB & Inoperable IIIC Treatment Options

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Treatment Options STAGE IIIB and Inoperable IIIC

tumor of any size with spread to tissues near the breast (skin of the breast or muscles or ribs of the chest wall), and possibly to lymph nodes in the area (IIIB) OR
inflammatory breast cancer (IIIB) OR
tumor of any size with spread to lymph nodes in or near the breast and to lymph nodes in or near the neck and above the collarbone (inoperable IIIC)

Treatment to the Breast

chemotherapy to shrink tumor and/or lymph nodes, followed by total mastectomy that may require removal of other nearby tissues involved with the tumor


radiation after mastectomy

Treatment to the Lymph Nodes

axillary lymph node removal by traditional approach


possible radiation to supraclavicular and/or internal mammary lymph nodes


chemotherapy almost always recommended

Hormonal Therapy

hormonal therapy used for people with hormone-receptor-positive cancer

Targeted Therapy

targeted therapy may be used for people with cancers that have certain characteristics (for example, cancers with too many HER2 protein receptors)

Treatment to Other Parts of the Body

does not apply

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