Making HRT Decisions With a History of Breast Cancer

Dr. Tara Sanft discusses why making a decision about using hormone replacement therapy is so complicated for people with a history of breast cancer.

Published on December 10, 2025

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At the 2025 San Antonio Breast Cancer Symposium (SABCS), Dr. Tara Sanft, associate professor of medicine at the Yale School of Medicine and director of the Yale Survivorship Clinic, moderated a session called “Balancing Act: Hormone Replacement Therapy in Breast Cancer Care.”

Listen to the episode to hear Dr. Sanft explain:

  • the difference between systemic and local HRT

  • why HRT decisions need to be nuanced and individualized for anyone with a history of breast cancer – there is no one-size-fits-all

  • her advice to people with a history of breast cancer who are considering HRT

Scroll down to below the “About the guest” information to read a transcript of this podcast.


About the guests
 
Tara Sanft heashot
Tara Sanft, MD

Tara Sanft, MD, is associate professor of medicine at the Yale School of Medicine and director of the Yale Survivorship Clinic. She is board-certified in both medical oncology and hospice and palliative medicine.

 

This podcast episode is made possible by Lilly.

 
 
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