comscoreStories of Genetic Testing, Prophylactic Surgery, and Reconstruction: Mandi

Stories of Genetic Testing, Prophylactic Surgery, and Reconstruction: Mandi

Mandi Seifert tested positive for a BRCA2 gene mutation. She chose prophylactic mastectomy and reconstruction.
Oct 19, 2016

Mandi Seifert was 3 when her mother was diagnosed with breast cancer in 1990. When it became available, genetic testing for a mutation that raises the risk of breast cancer was strongly recommended for Mandi’s mom — in 2010 her mother tested positive for a BRCA2 mutation. Mandi knew that meant she had a 50-50 chance of having the same mutation. In 2013, she decided to have genetic testing and learned that she, too, had a BRCA2 mutation. She decided to have a double prophylactic mastectomy and reconstruction using tissue from her tummy area.

Mandi’s older sister, Kerry, also tested positive for a BRCA2 mutation.

Listen to the podcast to hear Mandi discuss:

  • how talking about her surgery with her sister was both emotional and freeing

  • how it felt to see her reconstructive surgeon again after she was completely healed

  • how her sister’s experience helped guide her

  • why family support is so important

About the guest
Mandi Seifert

Mandi Seifert is one of three women whose stories are featured in the video series on genetic testing, prophylactic surgery, and reconstruction.

— Last updated on July 31, 2022, 10:20 PM

Center for Restorative Breast Surgery

This podcast episode made possible by the Center for Restorative Breast Surgery.

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